BPA exposure during pregnancy causes oxidative stress in child, mother

"Researchers analyzed blood samples from 24 mother and infant pairs to examine the effects of BPA exposure. The women had blood drawn during the first trimester of pregnancy to measure their BPA levels. The women were divided into two groups - those who had lower levels of BPA in their blood, and those who had higher levels. Researchers also took blood samples from the umbilical cords after the babies were delivered and measured the amount of chemical byproducts created by oxidative stress.
The blood analysis revealed that the human mothers exposed to higher levels of BPA and their infants showed signs of oxidative stress caused by overexposure to nitric oxide-derived free radicals. The study participants had larger amounts of byproducts caused by this type of oxidative damage in their blood.
In addition to the human subjects, the researchers studied the effects of BPA on pregnancy in sheep, rats and mice. The scientists fed animals diets containing either high or low doses of BPA. The researchers then measured the resulting oxidative stress on the mothers and their offspring using blood samples. The results corroborated the results in the human study."




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