Showing posts with label prostate cancer. Show all posts
Showing posts with label prostate cancer. Show all posts

Prostate 'organoid' hints at how early BPA exposure may increase cancer risk


Monoamine oxidase (MAOA) inhibitors could help researchers develop prostate cancer treatments -- ScienceDaily

The study, published in the Journal of Clinical Investigation,
found that suppressing the enzyme monoamine oxidase A, or MAOA, may
reduce or even eliminate prostate tumor growth and metastasis in
laboratory mice. The finding could open the door for physicians to use
antidepressants to fight prostate cancer. Currently, drugs that inhibit
MAOA enzymes are used to treat patients with mental illnesses like
depression.

BBC News - Prostate cancer 'may be a sexually transmitted disease'

Prostate cancer may be a sexually transmitted disease caused by a common yet often silent infection passed on during intercourse, scientists say - but experts say proof is still lacking. Although several cancers are caused by infections, Cancer Research UK says it is too early to add prostate cancer to this list.
The University of California scientists tested human prostate cells in the lab.
They found a sex infection called trichomoniasis aided cancer growth.
More research is now needed to confirm the link, they say in the journal Proceedings of the National Academy of Sciences (PNAS).

Here's the paper:-

Trichomonas vaginalis homolog of macrophage migration inhibitory factor induces prostate cell growth, invasiveness, and inflammatory responses


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BPA linked to prostate cancer, study shows

Findings by Cincinnati Cancer Center researchers show that levels of
bisphenol A (BPA) in men's urine could be a marker of prostate cancer
and that low levels of BPA exposure can cause cellular changes in both
non-malignant and malignant prostate cells.

Unusual combination therapy shows promise for preventing prostate cancer, researchers find

Combining a compound from broccoli with an antimalarial drug prevents prostate cancer in mice, University of Pittsburgh Cancer Institute (UPCI) researchers discovered.

Link between omega-3 fatty acids and increased prostate cancer risk confirmed

 "A second large, prospective study by scientists at Fred Hutchinson Cancer Research Center has confirmed the link between high blood concentrations of omega-3 fatty acids and an increased risk of prostate cancer."


Exposure to BPA in developing prostate increases risk of later cancer: Ubiquitous plasticizers may have long-term health effects

 "Early exposure to BPA (bisphenol A) -- an additive commonly found in plastic water bottles and soup can liners -- causes an increased cancer risk in an animal model of human prostate cancer, according to University of Illinois at Chicago researcher Gail Prins."


Exposure to BPA in developing prostate increases risk of later cancer

 "Early exposure to BPA (bisphenol A) – an additive commonly found in plastic water bottles and soup can liners – causes an increased cancer risk in an animal model of human prostate cancer, according to University of Illinois at Chicago researcher Gail Prins. Prins presented her findings at the ENDO 2013 meeting in San Francisco June 17."


Agent Orange Linked To Fatal Prostate Cancer

"A new study of US Veterans has found that exposure to Agent Orange is linked to a two-fold higher risk of developing the most lethal forms of prostate cancer. The researchers suggest a history of exposure to the agent, which contains the dioxin 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a dangerous toxin and carcinogen, should be one of the first things to look for when screening Veterans as it could lead to earlier diagnosis and treatment and prolong survival."

( Agent orange was liberally sprayed onto Vietnam, eastern Laos and parts of Cambodia during the Vietnam War) Wikipedia Agent Orange

Obesity promotes prostate cancer by altering gene regulation

Prostate cancer is one of the most common cancers in men and early treatment is usually very successful. However, like other cancers, obesity increases the risk of aggressive prostate disease. New research, published in BioMed Central's open access journalBMC Medicine, finds that the fat surrounding the prostate of overweight or obese men with prostate cancer provides a favorable environment to promote cancer growth.

MicrobeWorld - New Evidence for Polyomavirus BK Role in Prostate Cancer

Prostate cancer is the leading cause of cancer morbidity and the third greatest cause of cancer death among men in developed countries. A major question in cancer research has been whether virus infection plays a role in cancers of the genitourinary tract. Now a team of Swiss investigators has new evidence suggesting human polyomavirus BK is involved in maintaining and enhancing an environment suitable for prostate cancer growth. The research, published in the August Journal of Virology, could lead to preventive and/or therapeutic prostate cancer vaccines (click source to download a .pdf of the journal article).

Two viruses link to prostate cancer: High-risk human papilloma virus found with Epstein Barr virus

Two common viruses known to be associated with human cancers are both present -- and may even be collaborating with each other -- in most male prostate cancers, a new study suggests. The human papilloma virus (HPV) and Epstein Barr virus (EBV) were present in more than half of the malignant cancers, as well as in a high proportion of benign and normal prostate samples.

For advanced prostate cancer, new drug slows disease

A new medication (abiraterone acetate) proved effective in slowing the spread of metastatic prostate cancer, while helping to maintain the quality of life, in patients with advanced disease. The phase 3 study was unblinded midway, allowing patients receiving the placebo to instead take the drug because of the favorable results.

Futurity.org – Beehive remedy may slow prostate cancer

An over-the-counter remedy derived from honeybee hives stalls the growth of prostate cancer cells in mice.
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Oregano Kills Prostate Cancer? | Medical News and Health Information

The study is testing the ingredient carvacrol, found in oregano. The results demonstrate that the compound induces apoptosis in these cancer cells.
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Eating smart: Researcher studies foods, dietary supplements that may reduce risk of prostate cancer

A Kansas State University professor is turning to nutrition to tackle prostate cancer.Lindshield is studying different dietary supplements that affect prostate cancer risk. He is focusing on extract from saw palmetto, a type of shrub that looks similar to a palm tree. Many men take saw palmetto extract because it is believed to benefit prostatic health and inhibit the same enzymes as finasteride and . But a lack of regulation and research surrounding saw palmetto has not provided clear insight into whether taking the extract is beneficial.
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UNC scientists collaborate to find first major genetic mutation associated with hereditary prostate cancer risk

Age-standardised death rates from Prostate can...
Prostate cancer incidence Image via Wikipedia
The research team found that men who inherit this mutation in the homeobox protein HOXB13 have a 10 to 20 times higher risk of developing prostate cancer.
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Suggested link between The Pill and prostate cancer

AN international study published in BMJ Open has recently suggested the existence of a casual link between the use of the contraceptive pill and the increase incidence of prostate cancer, due to men’s abnormal exposure to low levels of oestrogen in the environment.
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