Free radicals 'do not cause aging, they combat it,' study suggests - Medical News Today

Past research has suggested that free radicals - occasionally
harmful molecules produced by the body as it processes oxygen -
contribute to the aging process. But new research from McGill University
in Canada finds that free radicals may actually increase lifespan
rather than shorten it.

Discovery offers molecular insights into link between Parkinson's and pesticides

Rotenone and paraquat, as well as MPTP inhibit various components of the mitochondrial respiratory chain, enough in itself to severely compromise substantia nigra neurones. The oxidative stress that ensues also oxidises Parkin, the product of a gene implicated in Parkinson's disease  , producing Parkin aggregation and malfunction.

Parkinson's disease genes risk factors and pathways

Stress takes its toll in Parkinson's disease

Calcium antagonists such as isradipine can reduce the mitochondrial oxidative stress in substantia nigra neurones, suggesting  a use for this class of drug in Parkinson's disease.

Access : O2 regulates stem cells through Wnt/|[beta]|-catenin signalling : Nature Cell Biology

Access : O2 regulates stem cells through Wnt/|[beta]|-catenin signalling : Nature Cell Biology

Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species — PNAS

An important link between free radical generation and the immune system, highlighting a role of free radicals as messengers and not simply as toxic species