MGAT1 regulates autoimmunity via T cell modulation Grigorian et al, 2007 and other mechanisms are discussed in this key paper
Multiple sclerosis genes risk factors and pathways
Showing posts with label glycomics. Show all posts
Showing posts with label glycomics. Show all posts
Genetics and the environment (Vitamin D) converge to dysregulate N-glycosylation in multiple sclerosis : Nature Communications : Nature Publishing Group
Susceptibility genes (IL2RA , IL7RA and CTLA4 ) and the protective environmental factor, Vitamin D3, pivot around a see-saw that controls the activity of a glycosylation enzyme, MGAT1 , whose increased activity decreases the risk of developing multiple sclerosis , with decreased activity increasing risk.
MGAT1 regulates autoimmunity via T cell modulation Grigorian et al, 2007 and other mechanisms are discussed in this key paper
Multiple sclerosis genes risk factors and pathways
MGAT1 regulates autoimmunity via T cell modulation Grigorian et al, 2007 and other mechanisms are discussed in this key paper
Multiple sclerosis genes risk factors and pathways
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