One minute ultraviolet exposure inhibits Toxoplasma gondii tachyzoite replication and cyst conversion without diminishing host humoral-mediated immune response.

We developed a protocol to inactivate Toxoplasma gondii (T. gondii)
tachyzoites employing 1 minute of ultraviolet (UV) exposure. We show
that this treatment completely inhibited parasite replication and cyst
formation in vitro and in vivo but did not affect the induction of a
robust IgG response in mice. We propose that our protocol can be used to
study the contribution of the humoral immune response to rodent
behavioral alterations following T. gondii infection.

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