The placebo effect, where treatments with no active ingredients help to alleviate symptoms in some patients and not others, has been a mystery to medical science for the last 70 years. Now for the first time, researchers in the US reporting in PLoS ONE this week, describe how they found clues that might explain why the placebo effect works for some people and not others: it's in their genes, they suggest. An important gene is catechol-O-methyltransferase (COMT).
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