Antibody test could detect Alzheimer's at preventable stage - Medical News Today

The research is presented this week by Dr. Robert Nagele, PhD, at the American Osteopathic Association's Osteopathic Medical Conference and Exposition (OMED15) in Orlando, FL.
It explains how autoantibodies act as blood-based biomarkers in order to detect numerous diseases and identify the stage to which a disease has progressed.
The work is based on the premise that thousands of autoantibodies are present in human blood (even in non-diseased individuals) . These specifically bind to blood-borne cellular debris generated by organs and tissues all over the body.
An individual's autoantibody profile depends on age, gender and the presence of specific diseases or injuries. Diseases cause characteristic changes in autoantibody profiles that, when detected, can serve as biomarkers that reveal the presence of the disease.

See also their  2011 paper
Diagnosis of Alzheimer's disease based on disease-specific autoantibody profiles in human sera.

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