Arsenic metabolism linked to diabetes incidence

Chin-Chi Kuo, M.D., M.P.H., from the Johns Hopkins Bloomberg
School of Public Health in Baltimore, and colleagues examined the
prospective association between low-moderate arsenic exposure and
arsenic metabolism with diabetes incidence. The investigators recruited
1,694 diabetes-free participants aged 45 to 75 years in 1989 to 1991 and
followed them through 1998 to 1999. The proportions of urine inorganic arsenic
(iAs), monomethylarsonate (MMA), and dimethylarsinate (DMA) over their
sum (expressed as iAs percent, MMA percent, and DMA percent) were used
as arsenic metabolism biomarkers.

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