Defects in fatty acid transport proteins linked to schizophrenia and autism | RIKEN

Using diverse methodologies, neuroscientists from the RIKEN Brain
Science Institute report that defects in Fatty Acid Binding Proteins
(FABPs) may help to explain the pathology in some cases of schizophrenia
and autism spectrum disorders. After identifying mutations in FABPs
from patients, the group led by Senior Team Leader Takeo Yoshikawa
determined that the genetic disruption of Fabps in mice mimics disease
behaviors seen in patients. This work suggests that disruption of FABPs
could be a common link underlying some forms of these two prevalent
mental disorders.

Here's the paper:-


Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies

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