Time Trends Over 16 Years in Incidence-Rates of Autism Spectrum Disorders Across the Lifespan Based on Nationwide Danish Register Data.

This study investigated time trends and associated factors of incidence
rates of diagnosed autism spectrum disorders (ASD) across the lifespan
from 1995 to 2010, using data from the Danish Psychiatric Central
Research Registry. First time diagnosis of childhood autism, atypical
autism, Asperger's syndrome, or pervasive developmental
disorder-unspecified (PDD-NOS) were identified, incidence rates were
calculated, and data were fitted using non-linear least squares methods.
A total of 14.997 patients were identified and incidence rates for ASD
increased from 9.0 to 38.6 per 100,000 person years during the 16-year
period. The increases were most pronounced in females, adolescents,
adults, and patients with Asperger's syndrome and PDD-NOS.

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