In yesterday's publication of Neuron, Gallo, who also is a
professor of pediatrics at the George Washington University School of
Medicine and Health Sciences (SMHS), reported identifying a small
protein that can be targeted to promote repair of damaged tissue, with
therapeutic potential. The molecule, Endothelin-1 (ET-1), is shown to
inhibit repair of myelin. Myelin damage is a hallmark characteristic of
MS. The study demonstrates that blocking ET-1 pharmacologically or using
a genetic approach could promote myelin repair.
professor of pediatrics at the George Washington University School of
Medicine and Health Sciences (SMHS), reported identifying a small
protein that can be targeted to promote repair of damaged tissue, with
therapeutic potential. The molecule, Endothelin-1 (ET-1), is shown to
inhibit repair of myelin. Myelin damage is a hallmark characteristic of
MS. The study demonstrates that blocking ET-1 pharmacologically or using
a genetic approach could promote myelin repair.
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