Stomach bacteria switch off human immune defences to cause disease

 : "Researchers from the University of Nottingham have shown that Helicobacter pylori is able to supress the body's normal production of 'human beta defensin 1' (DEFB1), an antimicrobial factor present in the stomach lining that helps prevent bacterial infection. By collecting stomach tissue biopsies from 54 patients at the Queens Medical Centre, Nottingham, the team showed that patients infected with H. pylori had ten times less DEFB1 than uninfected patients. Those with the lowest amount of DEFB1 had the most bacteria present in their stomach lining."
H.Pylori has been linked to gastritis, peptic ulcers and gastric cancer.

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