"Sustained low-grade inflammation and an above-average appetite are commonly found in obese individuals. Therefore, it seems counterintuitive that the acute inflammation associated with many illnesses normally suppresses appetite. A team led by Weiping Han of the Singapore Bioimaging Consortium at A*STAR has used mice to elucidate the molecular mechanisms that explain the different effects of chronic and acute inflammation on appetite. The study also helps to explain why obesity compromises appetite-suppression mechanisms."
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