A series of reviews on obesity from The Journal of Clinical Investigation

The World Health Organization estimates that 1 in 10 adults are obese, and as this epidemic expands world wide, the associated morbidities, including diabetes and heart disease, increase in prevalence as well. The reviews in this series make clear that obesity is a multi-organ, multi-system disease, with both genetic and environmental components. In addition, they highlight how recent breakthroughs in a variety of scientific fields – from an improved understanding the neural circuits that drive eating behavior to the identification of proteins that regulate fat storage- might lead to novel therapeutic strategies. Tweet