Slim down by targeting the hormone uroguanylin

Pro-uroguanylin is secreted by the gut in mice following a meal  , and travels to the satiety centre in the hypothalamus where conversion to uroguanylin suppresses food intake : This could lead to the development of appetite suppressants. However, drugs are not the way to fight the obesity epidemic and its causes need to be eliminated.

Childhood obesity genes and risk factors:
 
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