Scientists Map Changes In Genetic Networks Caused By DNA Damage - Science News - redOrbit

If you think that genes are static, and isolated , think again: Hundreds are wired together in signalling networks that change in many different epistatic ways in response to stress. I suppose this means that one SNP in one gene could affect the expression of hundreds of others. These could of course be more relevant that the seed gene. Analysis of signalling networks may be the way forward in disease gene analysis.