International Collaboration Amasses Largest Database To Advance Drug Development In Depression And Schizophrenia

This is a great spin-off of the genomics era. By comparing genomes in patients where the drug does or doesn't work, where there are more or less side effects, or where the placebo works, drugs may eventually be tailored to individuals. There may be no point in taking Prozac if your serotonin transporter is less sensitive to it, or of taking neuroleptics if you have a particular isoform of D2 receptor. DNA chips, and even whole genome sequencing for individuals will soon be an affordable reality allowing  more personalised, and hopefully more effective and less toxic therapies.

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