New Target for Aspirin and salicylate| The Scientist

Salicylate, the natural compound on which aspirin is based, directly activates a pathway linked to tumor suppression and glucose regulation, which may explain some of aspirin’s long-term health benefits, such as its role in cancer prevention. Published this week (April 19) in Science, the research shows that salicylate directly activates AMP kinase, which regulates a cell’s ATP levels, which in turn promotes fat burning in mice