The COPa knowledgebase is a resource of proteome biology configured specially for cardiovascular investigators. This project is developed under NHLBI proteomics center program with the partnership of Beijing Genomics Institute (BGI), European Bioinformatics Institute , Royal Institute of Technology (KTH), The Scripps Research Institute (TSRI), the Zhejiang University (ZJU) and UCLA. We hope it will serve as a useful tool for advancing cardiovascular biology and medicine.
The innovations in proteome biology offer unprecedented opportunities towards translational medicine. Advancing cardiovascular medicine requires an understanding of cardiac function at the systems level but with sufficient molecular details at the same time. Proteomics technologies are large scale in nature and their datasets come in various forms. The integration of these resources inspires innovative insights and bridges data-driven discoveries with hypothesis-driven investigations. The effective and comprehensive characterization of proteome biology holds the promise to advance cardiovascular medicine.
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