Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice : Nature Neuroscience

Small non-coding RNAs (sncRNAs) are potential vectors at the interface
between genes and environment. We found that traumatic stress in early
life altered mouse microRNA (miRNA) expression, and behavioral and
metabolic responses in the progeny. Injection of sperm RNAs from
traumatized males into fertilized wild-type oocytes reproduced the
behavioral and metabolic alterations in the resulting offspring.

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