Environmental factors can mitigate genetic risk for developing alcohol problems

ScienceDaily (Nov. 8, 2012) — Alcohol use during adolescence is harmful on multiple levels, including an increased risk for developing alcohol use disorders (AUDs) later in life. Recent research suggests that genetic influences are moderated by environmental factors. A new study of gene-environment interactions between a functional single nucleotide polymorphism (SNP) of the μ-opioid receptor (OPRM1) gene (A118G) and the risk for developing an AUD during adolescence, with a specific focus on the influence of parenting practices or affiliation with deviant peers, has confirmed that environmental factors can moderate this association.

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