Researchers identify new group of proteins in the brains of Alzheimer's patients

The researchers identified a new group of proteins, termed RNA-binding proteins, which accumulate in the brains of patients with Alzheimer's disease, and are present at much lower levels in subjects who are cognitively intact. The group found two different proteins, both of which show striking patterns of accumulation. "Proteins such as TIA-1 and TTP, accumulate in neurons that accumulate tau protein, and co-localize with neurofibrillary tangles. These proteins are a component off stress granules.