Multiple sclerosis
Measles IgG antibody index correlates with t2 lesion load on MRI in patients with early multiple sclerosis.
B cells and humoral immune responses play an important role in the
pathogenesis and diagnosis of multiple sclerosis (MS). A characteristic
finding in patients with MS is a polyspecific intrathecal B cell
response against neurotropic viruses, specifically against measles
virus, rubella virus, and varicella zoster virus, also known as an MRZ
reaction (MRZR). Here, we correlated from the routine clinical
diagnostics individual IgG antibody indices (AIs) of MRZR with magnetic
resonance imaging (MRI) findings in patients with first MS diagnosis.
Multiple sclerosis
Multiple sclerosis
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