Concerning the relationships between genes, risk factors and immunity in Alzheimer's disease, Autism, Bipolar disorder , multiple sclerosis, Parkinson's disease, schizophrenia and chronic fatigue
JARID1 turns on the circadian circuit by forming a complex with known clock genes, CLOCK and BMAL1. The complex in turn spurs the production of PER—a protein whose expression follows a 24-hour cycle—every morning when PER levels are low.
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