Lyme disease, caused by Borrelia burgdorferi is a tick borne infection associated with many diseases, including Alzheimer's disease and schizophrenia. Antibodies to the pathogen persist even after its elimination and could be responsible for the immune activation seen in patients.
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The results of all these studies when taken together allow us to conclude that Borrelia burgdorferi and oral spirochetes can persist in the brain and in analogy to Treponema pallidum, can cause dementia, cortical atrophy and amyloid deposition. Exposure to bacteria or to their toxic products, host responses similar in nature to those observed in AD may be induced. Bacteria and/or their degradation products may initiate a cascade of events leading to cell death, neurodegeneration and amyloid deposition in AD. As a consequence may cause cortical atrophy, amyloid deposition and dementia.
http://www.miklossy.ch/452/index.html
Just recently published further work by Judith Miklossy
Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria.
http://www.jneuroinflammation.com/content/8/1/90/abstract
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