Ketamine’s Antidepressant Effect Explained - Science News
It upregulates BDNF expression : This could be a fast acting antidepressant (most take months to work) , but NMDA antagonists are not without their own problems - including an ability to promote pyschosis, and some of these channel blockers also cause vacuolisation in cortical areas - reason enough to halt their development as neuroprotective compounds for stroke a few years ago.
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