Charting the peptide crossreactome between HIV-1 a... [Front Biosci (Elite Ed). 2011] - PubMed result

The HIV-1 proteome shares extensive homology with human proteins, including those involved in AIDS, or with the comorbid conditions associated with AIDS (psychosis, myopathy, cardiovascular disorders, hypertension, corneal diseases, diarrhea, lymphoma, and bladder cancer).
The findings are relevant to HIV-1 escape from immune surveillance, adjuvant-induced HIV-1 immunogenicity, and autoimmune cross-reactivity following human hyperimmune responses against HIV-1, and AIDS.
This phenomenon is also common to other viruses and bacteria, whose proteins resemble those relevant to the pathologies of the diseases in which they are implicated - for example herpes simplex and Alzheimer's disease, or diverse pathogens and schizophrenia.
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