A high Cholesterol diet in rats produces most of the symptoms of Alzheimer's disease including memory loss, cholinergic dysfunction, inflammation, beta-amyloid deposition and tau phosphorylation.
These environmental risk factors thus appear to be much more important than the genes, although these evidently define our susceptibility to factors such as hypercholesterolemia. Another risk factor, herpes simplex also causes entorhinal cortex and hippocampal damage along with memory loss in mice Armien et al, 2010 : We can't do anything about our genes, but the risk factors can be attacked.
cholesterol diet
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