Nerve growth factor maintains Herpes simplex in a latent state. This is important as the virus can have protective anti-apoptosis effects during latency and can also promote neurite extension in neuroblastoma cells Li et al, 2010
Herpes simplex has been implicated in Alzheimer's and other diseases and latency promotion is of interest.
Interactions between Herpes simplex and the products of Alzheimer's disease susceptibility genes are annotated here
In addition there is a database of Herpes simplex/host interactions here
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