However, note that PICALM did not turn up positive in a chinese study Yu et al, 20101 supporting the notion that genetic associations may cluster in geographical hot and cold spots. See database
Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
This study confirmed APOE , clusterin , complement receptor 1 and PICALM, and also angiotensin converting enzyme ACE and cystatin CST3 as Alzheimer's disease risk factors
However, note that PICALM did not turn up positive in a chinese study Yu et al, 20101 supporting the notion that genetic associations may cluster in geographical hot and cold spots. See database
However, note that PICALM did not turn up positive in a chinese study Yu et al, 20101 supporting the notion that genetic associations may cluster in geographical hot and cold spots. See database
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