Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ) deposition — PNAS

Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ) deposition — PNAS "..................the spatial distribution of aerobic glycolysis in normal young adults correlates spatially with Aβ deposition in individuals with DAT and cognitively normal participants with elevated Aβ, suggesting a possible link between regional aerobic glycolysis in young adulthood and later development of Alzheimer pathology". CMR glu is reduced prior to discernible symptoms in Alzheimer's disease (Cutler 1986) and correlates with deficits in AD patients Rapoport 1986